bromodiphenhydramine

Ligand id: 7132

Name: bromodiphenhydramine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 6
Topological polar surface area 12.47
Molecular weight 333.07
XLogP 5.53
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used to treat the symptoms of many allergic conditions.
Mechanism Of Action and Pharmacodynamic Effects
Bromazine blocks the action of endogenous histamine at the histamine H1 receptor. This drug may also have anticholingeric /antimuscarinic action which is likely to account for the drug causing drowsiness.