carteolol

Ligand id: 7142

Name: carteolol

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 6
Topological polar surface area 74.08
Molecular weight 292.18
XLogP 2.09
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used to treat hypertension and to reduce intraocular pressure.
Mechanism Of Action and Pharmacodynamic Effects
Carteolol blocks catecholamine stimulation of β1- and β2-adrenoceptors in the heart to lower the heart rate and blood pressure. This antagonism probably also initiates a decrease in aqueous humor production to relieve intraocular pressure.
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