dapiprazole

Ligand id: 7155

Name: dapiprazole

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 4
Topological polar surface area 37.19
Molecular weight 325.23
XLogP 3.72
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used to constrict the pupil, usually to reverse mydriasis induced for eye examination.
Mechanism Of Action and Pharmacodynamic Effects
Dapiprazole is an antagonist of smooth muscle α-1a adrenoceptors. When applied locally to the eye, the drug causes constriction of the sphincter of the iris, reducing pupil size.