diphenidol

Ligand id: 7163

Name: diphenidol

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 23.47
Molecular weight 309.21
XLogP 6.78
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Diphenidol is used as an antiemetic. This drug is not approved for clinical use in the US or EU. Other national approval agencies may have granted marketing authorisation.
Mechanism Of Action and Pharmacodynamic Effects
ChEMBL list this drug as an antagonist of the muscarinic acetylcholine receptor M1 (CHRM1), but its precise mechanism of action is poorly understood. See the DrugBank link for further details.