Ligand id: 7175

Name: enflurane

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 0
Rotatable bonds 3
Topological polar surface area 9.23
Molecular weight 183.97
XLogP 2.49
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Enflurane is an inhalation anesthetic.
Mechanism Of Action and Pharmacodynamic Effects
Enflurane perturbs membrane fluidity and alters the activity of many ion channels and receptors required for cell-cell signalling across gap junctions and which underlie the action potential. In this way the drug induces generalised muscle relaxation and sensitivity to pain.