Ligand id: 7196

Name: hexylcaine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 38.33
Molecular weight 261.17
XLogP 4.89
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used as a short-acting local anaesthetic. However, there is no information regarding approval for clinical use of this drug on the US FDA website. Other national approval agencies may have granted marketing authorisation.
Mechanism Of Action and Pharmacodynamic Effects
This drug blocks sodium channel α subunits in peripheral nerve endings (genes SNC1A-SNC11A are listed in this database in the voltage-gated sodium channels section). This reduces action potential generation and blocks nerve signal propagation. See the DrugBank link for further details.