Ligand id: 7205

Name: isoetarine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 4
Rotatable bonds 5
Topological polar surface area 72.72
Molecular weight 239.15
XLogP 1.63
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used to treat emphysema, bronchitis, chronic obstructive pulmonary disease (COPD) and asthma.
Mechanism Of Action and Pharmacodynamic Effects
Isoetarine is a selective β2-adrenoceptor agonist. Agonist-induced receptor activation increases cAMP levels which relaxes bronchial smooth muscle, and inhibits release of mediators of immediate hypersensitivity (eg histamine, leukotrienes, and prostaglandin) from mast cells.