levobupivacaine

Ligand id: 7211

Name: levobupivacaine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 35.83
Molecular weight 288.22
XLogP 4.91
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used for surgical anaesthesia and pain management. However, there is no information regarding approval for clinical use of this drug on the US FDA website. Other national approval agencies may have granted marketing authorisation.
Mechanism Of Action and Pharmacodynamic Effects
This drug acts by blocking sodium channel α subunits, potentially SCN4A. This reduces action potential generation and blocks nerve signal propagation.
External links