Ligand id: 7228

Name: mesuximide

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 1
Topological polar surface area 37.38
Molecular weight 203.09
XLogP 2.57
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Mesuximide is an anticonvulsant drug used to control petit mal seizures. However, there is no information regarding approval for clinical use of this drug on the US FDA website. Other national approval agencies may have granted marketing authorisation
Mechanism Of Action and Pharmacodynamic Effects
Mesuximide blocks activity of transient (T-type) voltage gated calcium channels. CACNA1E, CACNA1H and CACNA1I alpha subunits are detailed in this database, in the voltage-gated calcium channels section. See the DrugBank link for further details explaining the predicted molecular mechanism of action of this drug.