Ligand id: 7234

Name: methoxyflurane

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 0
Rotatable bonds 2
Topological polar surface area 9.23
Molecular weight 163.96
XLogP 1.91
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Methoxyflurane is an inhalation anaesthetic.
Mechanism Of Action and Pharmacodynamic Effects
Methoxyflurane perturbs membrane fluidity and alters the activity of many ion channels and receptors required for cell-cell signalling across gap junctions and which underlie the action potential. In this way the drug induces generalised muscle relaxation and insensitivity to pain. See the DrugBank link for further details.
Due to the complex nature of this drug's MMOA, we do not tag a primary drug target.
External links