midodrine

Ligand id: 7240

Name: midodrine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 6
Topological polar surface area 97.3
Molecular weight 254.13
XLogP -0.26
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used to treat hypotension.
Mechanism Of Action and Pharmacodynamic Effects
Desglymidodrine is an α1-adrenoceptor agonist. Activation of α-adrenoceptors causes vasoconstriction which acts to increase blood pressure. However, we have been unable to find affinity data for this drug to substantiate its MMOA.
External links