oxazepam

Ligand id: 7253

Name: oxazepam

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 1
Topological polar surface area 65.18
Molecular weight 286.05
XLogP 4.37
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used in the treatment of anxiety, insomnia and alcohol withdrawl.
Mechanism Of Action and Pharmacodynamic Effects
Oxazepam positively modulates the activity of GABAA anion channels. The drug increases inhibitory GABAergic tone and causes neuro-inhibition. Drug-induced effects are observed clinically as anxiolytic, sedative, anticonvulsant and skeletal muscle relaxant actions.
External links