pirbuterol

Ligand id: 7272

Name: pirbuterol

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 4
Rotatable bonds 5
Topological polar surface area 85.61
Molecular weight 240.15
XLogP 0.55
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used to relieve asthmatic bronchospasm.
Mechanism Of Action and Pharmacodynamic Effects
Pirbuterol is an agonist of β2-adrenoceptors. Activation of these receptors increases cAMP levels which causes downstream relaxation of bronchial smooth muscle and inhibition of release of mediators of immediate hypersensitivity from cells such as mast cells.
External links