Ligand id: 7280

Name: procyclidine

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 23.47
Molecular weight 287.22
XLogP 5.6
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Procyclidine is used to treat the akathisia associated with Parkinson's disease or drug-induced Parkinsonism, and dystonias.
Mechanism Of Action and Pharmacodynamic Effects
Procyclidine is an anticholinergic drug, antagonising parasympathetic muscarinic acetylcholine receptor activity. This drug’s molecular mechanism of action (MMOA) is complex and not fully resolved. See the DrugBank link for further details.
External links