quazepam

Ligand id: 7288

Name: quazepam

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 3
Topological polar surface area 47.69
Molecular weight 386.03
XLogP 5.87
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Quazepam is used to treat insomnia.
Mechanism Of Action and Pharmacodynamic Effects
Quazepam selectively targets the GABAA α1 receptor subunit (GABRA1), which is responsible for inducing sleep. Drug treatment increases inhibitory GABAergic tone and causes neuro-inhibition, including sedation.
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