remifentanil

Ligand id: 7292

Name: remifentanil

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View more information in the IUPHAR Pharmacology Education Project: remifentanil

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 10
Topological polar surface area 76.15
Molecular weight 376.2
XLogP 2.36
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
May be combined with other medications to induce/maintain general anesthesia and to provide analgesia in mechanically ventilated intensive care patients.
Mechanism Of Action and Pharmacodynamic Effects
Agonist activity at the opioid receptors in the central nervous system (CNS) causes hyperpolarization and reduced neuronal excitability by various mechanisms. See the DrugBank link for further details.
External links