Synonyms: GI-87084B | Ultiva®
remifentanil is an approved drug (FDA (1996))
Compound class:
Synthetic organic
Comment: Remifentanil is a synthetic opioid analgesic drug.
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖View more information in the IUPHAR Pharmacology Education Project: remifentanil |
|
No information available. |
Summary of Clinical Use |
May be combined with other medications to induce/maintain general anesthesia and to provide analgesia in mechanically ventilated intensive care patients. |
Mechanism Of Action and Pharmacodynamic Effects |
Agonist activity at the opioid receptors in the central nervous system (CNS) causes hyperpolarization and reduced neuronal excitability by various mechanisms. See the DrugBank link for further details. |
External links |
For extended ADME data see the following: Electronic Medicines Compendium (eMC) Drugs.com |