Synonyms: Tonocard® | W-36095
tocainide is an approved drug (FDA (1984))
Compound class:
Synthetic organic
Comment: Tocainide is a lidocaine analog.
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No information available. |
Summary of Clinical Use |
Tocainide is used to treat serious cardiac arrhythmias. Use has been discontinued in the US, but other national approval agencies may continue marketing authorisation. |
Mechanism Of Action and Pharmacodynamic Effects |
This drug stabilises the cardiac membrane by binding to sodium channels, and decreasing permeability to Na+ ions. This blocks initiation and conductance of nerve impulses. ChEMBL report that this drug acts by blocking sodium channel α subunits (genes SNC1A-SNC11A) are listed in this database in the Voltage-gated sodium channels section. |