Ligand id: 7323

Name: chlormezanone

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 1
Topological polar surface area 62.83
Molecular weight 273.02
XLogP 1.27
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used to treat anxiety and muscle spasm. However, marketing was ceased worldwide in 1996 due to severe adverse reactions.
Mechanism Of Action and Pharmacodynamic Effects
The drug allosterically potentiates binding of inhibitory GABA to GABAA channels, resulting in inhibition of cortical and limbic arousal levels.
External links