hydralazine

Ligand id: 7326

Name: hydralazine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 0
Topological polar surface area 50.41
Molecular weight 160.07
XLogP 1.79
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used to treat hypertension and severe congestive cardiac failure.
Mechanism Of Action and Pharmacodynamic Effects
The molecular mechanism of action of this drug has not been fully resolved, but appears to involve vasodilatory action which improves cardiac oxygenation and reduces its workload. See the DrugBank link for further details.
External links