pemirolast

Ligand id: 7329

Name: pemirolast

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 1
Topological polar surface area 74.77
Molecular weight 228.08
XLogP 1.37
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Pemirolast is contained in opthalmic solutions used to treat the symptoms of seasonal allergic conjunctivitis, including itching, redness and swelling.
Mechanism Of Action and Pharmacodynamic Effects
Pemirolast blocks the action of endogenous histamine at histamine H1 receptor. The drug inhibits eosinophil infiltration in the eye and prevents their release of inflammatory mediators.
External links