Ligand id: 7349

Name: ospemifene

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 1
Rotatable bonds 8
Topological polar surface area 29.46
Molecular weight 378.14
XLogP 9.9
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Ospemifene is approved to treat pain during sexual intercourse (dyspareunia) in post-menopausal women.
Mechanism Of Action and Pharmacodynamic Effects
Ospemifene acts at estrogen receptors, mimicking the action of estrogen on the vaginal epithelium, reversing post-menopausal effects of vulval and vaginal atrophy [1].
External links