luliconazole

Ligand id: 7366

Name: luliconazole

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 2
Topological polar surface area 92.21
Molecular weight 352.96
XLogP 4.24
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used in the treatments of fungal infections caused by Trichophyton rubrum and Epidermophyton floccosum.
Mechanism Of Action and Pharmacodynamic Effects
The exact mechanism of action of luliconazole is unknown but it is thought to inhibit the enzyme lanosterol demethylase, thereby preventing the synthesis of ergosterol and disrupting fungus cell membrane synthesis.