iodipamide

Ligand id: 7400

Name: iodipamide  

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 4
Rotatable bonds 11
Topological polar surface area 132.8
Molecular weight 1139.51
XLogP 6.53
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Iodine contaning compound used as a contrast medium to visualise the hepatic and common bile ducts (cholecystography and intravenous cholangiography procedures). There is no information regarding approval for clinical use of this drug on the US FDA or European Medicines Agency websites. Individual national agencies may have granted marketing authorisation.
Mechanism Of Action and Pharmacodynamic Effects
The compound enters the liver from the blood stream and is secreted in to the bile shortly after administration. As the iodine content of the compound renders it radio-opaque, this allows visualisation of the biliary ducts and gallbladder under x-ray, with opacity proportional to the total amount of contrast agent present in the organs.