phenacetin

Ligand id: 7402

Name: phenacetin

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 38.33
Molecular weight 179.09
XLogP 2.02
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Was used for its antipyretic and analgesic properties, but was alleged to cause unacceptable side effects, notably analgesic nephropathy.
Mechanism Of Action and Pharmacodynamic Effects
Acts in a similar way to paracetamol and/or acts as paracetamol. See our entry for paracetamol for a description of the proposed molecular mechanism of action.