eribaxaban

Ligand id: 7408

Name: eribaxaban

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 2
Rotatable bonds 8
Topological polar surface area 90.98
Molecular weight 484.13
XLogP 3.7
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
A Phase 2 study after total knee replacement surgery was reported in 2013 [2] . The dose-response relationship for thromboembolism and bleeding using an adaptive study design provided a basis for Phase 3 dose selection.