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Synonyms: ACT-078 | Eloxatin®
oxaliplatin is an approved drug (FDA (2002))
Compound class:
Synthetic organic
Comment: Oxaliplatin is a platinum-based chemotherapy drug in the same class as carboplatin and cisplatin. Its main action is as a nucleic acid alkylating agent (see Clinical Data tab for further details). It is a platinum-chelating molecular complex (see CID 9887053).
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| No information available. |
Summary of Clinical Use  |
| Oxaliplatin is used in combination with other cancer medications to treat colon and rectal cancer. |
| Mechanism Of Action and Pharmacodynamic Effects |
| Oxaliplatin acts in several ways to interfere with DNA/RNA synthesis and replication and cell division, and to cause DNA mutation and damage, all of which lead to cell death/apoptosis. Due to the complex and varied nature of nucleic acids we do not include DNA or RNA as targets on this database. |
| External links |
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For extended ADME data see the following: Electronic Medicines Compendium (eMC) Drugs.com |
