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Synonyms: AF37702 | Hematide® | Omontys®
peginesatide is an approved drug (FDA (2012))
Compound class:
Peptide or derivative
Comment: Peginesatide is a PEGylated functional analogue of erythropoietin.
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
| No information available. |
Summary of Clinical Use  |
| Approved to treat anemia associated with chronic kidney disease (CKD) in dialysis patients. The administered drug contains the acetate salt. |
| Mechanism Of Action and Pharmacodynamic Effects |
| Peginesatide is an erythropoietin receptor agonist. This drug mimics the structure of human erythropoietin in promoting red blood cell development. |
| External links |
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For extended ADME data see the following: Drugs.com |
