deferiprone

Ligand id: 7456

Name: deferiprone

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 0
Topological polar surface area 40.54
Molecular weight 139.06
XLogP 0.35
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Patients with thalassaemia often require repeated blood transfusions to maintain red blood cell levels, but this type of treatment can lead to potentially fatal iron overload.
Mechanism Of Action and Pharmacodynamic Effects
Deferiprone chelates the excess iron in thalassemia patients [1], and effects its removal and excretion.
External links