dutasteride

Ligand id: 7457

Name: dutasteride

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 5
Topological polar surface area 58.2
Molecular weight 528.22
XLogP 7.91
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Approved for the treatment of benign prostatic hyperplasia (BPH) symptoms.
Mechanism Of Action and Pharmacodynamic Effects
Dutasteride is a 5α-reductase inhibitor, blocking the enzymatic conversion of testosterone to dihydrotestosterone (DHT).
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