Ligand id: 7466

Name: bepotastine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 8
Topological polar surface area 62.66
Molecular weight 388.16
XLogP 3.99
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Approved to treat allergic rhinitis and urticaria/pruritus. Bepotastine ophthalmic is used to treat itchy/watery eyes caused by allergies.
Mechanism Of Action and Pharmacodynamic Effects
Bepotastine is a non-sedating, selective antagonist of the histamine H1 receptor. The drug blocks the pro-inflammatory action of endogenous histamine at the histamine H1 receptor.
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