azelaic acid

Ligand id: 7484

Name: azelaic acid

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 8
Topological polar surface area 74.6
Molecular weight 188.1
XLogP 1.71
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Azelaic acid is applied topically to the skin to treat acne and rosacea.
Mechanism Of Action and Pharmacodynamic Effects
Azelaic acid is believed to have antimicrobial action plus an anti-inflammatory effect which modulates follicular hyperkeratosis, as the MMOA for the drug's therapeutic efficacy in acne and rosacea.
External links