Ligand id: 7562

Name: prasugrel

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 6
Topological polar surface area 74.85
Molecular weight 373.11
XLogP 3.68
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Prasugrel is used to prevent to prevent atherothrombotic events in patients with acute coronary syndrome (eg unstable angina, heart attack) undergoing percutaneous coronary intervention. It may also be used in patients with certain disorders of the heart or blood vessels.
Mechanism Of Action and Pharmacodynamic Effects
R-138727 is an antagonist of the P2Y12 receptor, which is an adenosine diphosphate (ADP) receptor expressed on platelets. ADP-induced activation of P2Y12 causes platelet aggregation and promotes blood clot formation. Antagonism of ADP binding inhibits these effects.
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