Summary of Clinical Use

Used to treat allergic conditions such as hay fever or urticaria. Drugs@FDA lists oral, single agent dexbrompheniramine medications as discontinued. Individual national approval agencies may have granted marketing authorisation for this drug.

Mechanism Of Action and Pharmacodynamic Effects

Dexbrompheniramine blocks the action of endogenous histamine at the histamine H1 receptor. This drug may also have anticholingeric /antimuscarinic action which is likely to contribute to the drug's side effects, which include drowsiness, dry mouth and throat and increased heart rate.