Ligand id: 7589

Name: ceruletide

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 33
Hydrogen bond donors 17
Rotatable bonds 47
Topological polar surface area 585.08
Molecular weight 1351.45
XLogP -2.44
No. Lipinski's rules broken 3

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used in paralytic ileus and as diagnostic tool in pancreatic malfunction. However, there is no information regarding approval of ths drug on either the US FDA or EMA websites. Individual national approval agencies may have granted marketing authorisation for this drug.
Mechanism Of Action and Pharmacodynamic Effects
Ceruletide is a peptidomimetic of cholecystokinin, acting as a cholecystokinin CCK1 receptor agonist. Drug action stimulates gastric, biliary, and pancreatic secretion of substances required for the digestion of fat and protein.