Ligand id: 805

Name: aplaviroc

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 3
Rotatable bonds 10
Topological polar surface area 119.41
Molecular weight 577.32
XLogP 6.12
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

No information available.
Mechanism Of Action and Pharmacodynamic Effects
CCR5 is a co-receptor for HIV-1 and other viruses, allowing these viruses to enter cells. Antagonism would be posulated to reduce viral entry to the cells.