epacadostat

Ligand id: 8221

Name: epacadostat

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 5
Rotatable bonds 8
Topological polar surface area 155.32
Molecular weight 436.99
XLogP 0.81
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
INCB024360 is in Phase II clinical development as an antineoplastic agent in patients with various solid tumours such as melanoma, ovarian, fallopian tube, or primary peritoneal cancers, and one study for myelodysplastic syndromes has been completed. Click here to link to ClinicalTrials.gov's complete list of Phase II INCB024360 trials.