Ligand id: 8917

Name: AMG319

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 4
Topological polar surface area 92.27
Molecular weight 385.15
XLogP 3.78
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
AMG319 is being evaluated in Phase II clinical trial for its potential as a treatment for human papillomavirus (HPV) negative head and neck squamous cell carcinoma (HNSCC)- see NCT02540928.