CE-326597

Ligand id: 9055

Name: CE-326597

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 1
Rotatable bonds 9
Topological polar surface area 87.12
Molecular weight 594.27
XLogP 9.86
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

No information available.
Mechanism Of Action and Pharmacodynamic Effects
One of the physiological functions of ehdogenous cholecystokinin (CCK) in the gut is promotion of satiety resulting in suppression of food intake. Activation of the CCK type A receptor by pharmacoligical agonists would be expected to mimic this satiety-inducing effect. This could help reduce food intake in obese patients.