clobetasone

Ligand id: 9088

Name: clobetasone

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 2
Topological polar surface area 71.44
Molecular weight 408.15
XLogP 1.38
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Can be used in adults and children for the relief of the inflammatory and pruritic manifestations of steroid responsive dermatoses such as:
- atopic dermatitis
- irritant or allergic contact dermatitis
- seborrhoeic dermatitis
- nappy rash
- photodermatitis
- otitis externa
- prurigo nodularis
- insect bite reactions
Mechanism Of Action and Pharmacodynamic Effects
Clobetasone is a glucocorticoid receptor agonist.