Ligand id: 9420

Name: esflurbiprofen

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 3
Topological polar surface area 37.3
Molecular weight 244.09
XLogP 5.51
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Approved in Japan; indicated for the relief of inflammation and pain associated with osteoarthritis. list Phase 2 trial NCT02729207 which is evaluating esflurbiprofen in hydrogel patch form for local analgesia in ankle sprains.