Synonyms: Bis-(3'-5')-cyclic dimeric guanosine monophosphate | c-di-GMP | cGpGp | dyclic diguanylate monophosphate
Compound class:
Synthetic organic
Comment: Cyclic di-GMP is a dinucleotide of bacterial origin that acts as a signalling molecule in prokaryotes. In mammals it acts as a STING (stimulator of IFN genes) agonist that promotes the type I interferon inflammatory response [1-2].
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Immunopharmacology Comments |
Induces STING activation and the innate type interferon response. |