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Molecular properties generated using the CDK |
Immunopharmacology Comments |
Experimental evidence indicates that P2Y12 receptors play a critical role in Th17 differentiation (in mouse models of autoimmune inflammatory diseases), and that P2Y12-selective antagonists reverse Th17 differentiation and ameliorate inflammatory sequelae [2]. These findings suggest potential for P2Y12 antagonists as therapeutics for autoimmune diseases. |