IFN-κ

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Ligands
IFN-κ (Human)

GtoPdb Ligand ID: 4969

Synonyms: interferon kappa

Compound class: Endogenous peptide in human, mouse or rat

Comment: IFN-κ is a type I IFN.

Species: Human

Summary
Biological activity
References
Structure
Immunopharmacology

Immunopharmacology Comments
IFN-κ is produced by human keratinocytes [1-2]. Like other type I IFNs, IFN-κ binds the IFN-α/β receptor (IFNAR), a dimeric receptor that consists of protein chains encoded by the IFNAR1 and IFNAR2 genes, and induces expression of proteins containing ISRE or GAS transcription elements.

Immunopharmacology Comments

IFN-κ is produced by human keratinocytes [1-2]. Like other type I IFNs, IFN-κ binds the IFN-α/β receptor (IFNAR), a dimeric receptor that consists of protein chains encoded by the IFNAR1 and IFNAR2 genes, and induces expression of proteins containing ISRE or GAS transcription elements.