tofacitinib

Ligand id: 5677

Name: tofacitinib

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 88.91
Molecular weight 312.17
XLogP 0.31
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Immunopharmacology Comments
Tofacitinib modulates both innate and adaptive immune responses [7].
Immunopharmacology Disease
Disease X-Refs Comment References
Rheumatoid arthritis Disease Ontology: DOID:7148
OMIM: 180300
Approved drug for RA.