IL-25

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Ligands
IL-25 (Human)

GtoPdb Ligand ID: 5876

Synonyms: IL-17E | interleukin-17E | interleukin-25

Compound class: Endogenous peptide in human, mouse or rat

Comment: IL-25 shares sequence similarity with IL-17 family proteins, and shares the IL17RB cytokine receptor with IL-17B.

Species: Human

Summary
Biological activity
References
Structure
Immunopharmacology

Immunopharmacology Comments
IL-25 is secreted by Th2 cells and mast cells and is able to induce production of IL-4, -5 and -13 which causes expansion of eosinophils. It is associated with gut immune regulation [2] and has potent antitumor activity in vivo [1].

Immunopharmacology Comments

IL-25 is secreted by Th2 cells and mast cells and is able to induce production of IL-4, -5 and -13 which causes expansion of eosinophils. It is associated with gut immune regulation [2] and has potent antitumor activity in vivo [1].