Ligand id: 8006

Name: BX-795

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 9
Hydrogen bond donors 4
Rotatable bonds 12
Topological polar surface area 139.52
Molecular weight 591.09
XLogP 3.98
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Immunopharmacology Comments
BX-795 is a low potency inhibitor of TBK1 in vitro (IC50 1000nM) [2], but has no in vivo efficacy [3].