Ligand id: 9180

Name: C108297

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 9
Topological polar surface area 82.04
Molecular weight 553.24
XLogP 5.58
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Immunopharmacology Comments
C108297 is a selective GR modulator which attenuates inflammation by reduced macrophage infiltration and pro-inflammatory cytokine expression in adipose tissue, and in RAW 264.7 macrophages [2].