Ligand id: 9323

Name: DMAT

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 1
Topological polar surface area 31.92
Molecular weight 472.74
XLogP 3.52
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Immunopharmacology Comments
DMAT-induced CK2 inhibition prevents TH17 cell development and promotes Treg cell generation, confirming CK2 as a target for pharmaceutical intervention and development of novel treatments for TH17 cell-driven autoimmune diseases [3].