Ligand id: 9450

Name: avacopan

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 9
Topological polar surface area 61.44
Molecular weight 581.27
XLogP 8.86
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Immunopharmacology Comments
Small molecule antagonist of human C5a1 receptor; in Phase III clinical trials for pancreatic cancer treament.