Ligand id: 9516

Name: CHMFL-BTK-11

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 80.12
Molecular weight 423.17
XLogP 3.59
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Immunopharmacology Comments
CHMFL-BTK-11 ameliorates the inflammatory response through blockage of proliferation of activated B cells and inhibition of the secretion of the inflammatory factors and represents a pharmacological tool for investigating BTK mediated signaling in rheumatoid arthritis (RA) [1].
Immunopharmacology Disease
Disease X-Refs Comment References
Rheumatoid arthritis Disease Ontology: DOID:7148
OMIM: 180300
A pharmacological tool suitable for investigating BTK mediated signaling in RA.